Multiscale modelling of glioma growth and treatments
Computational simulations of tumour growth before (left), one day after (middle) and 100 days after surgery (color bar shows intensity). This shows that the underlying mathematical model predict the multifocal regrowth of tumour after surgery as observed clinically

Gliomas, the most common primary brain tumours, are diffusive and highly invasive. The standard treatment for brain tumours consists of a combination of surgery, radiation therapy and chemotherapy. Currently, I am developing a multiscale mathematical model for glioma growth using several patient-specific information to assist its treatment planning and delivery.

Relevant Publications:
  • G. Powathil, M. Kohandel, S. Sivaloganathan, A. Oza, M. Milosevic, Mathematical modeling of brain tumor: effects of surgery, radiotherapy and chemotherapy, Physics in Medicine and Biology 2007, 52:3291, doi: 10.1088/0031-9155/52/11/023